Ryuichi Kambayashi, Ai Goto, Akira Takahara , Hiroyuki Saito , Hiroko Izumi-Nakaseko , Yoshinori Takei , Yasuki Akie , Masaaki Hori, Atsushi Sugiyama ; Characterization of remodeling processes in the atria of atrioventricular block dogs: Utility as an early-stage atrial fibrillation model. Journal of Pharmacological Sciences 156 (2024) 19–29
Tsuchiya K, Hayashi Y, Ryu S, Tran HT, Takano M, Tanaka K, Mizushima D, Oka S, Gatanaga H, Hamada A. ; Determination of intracellular tenofovir-diphosphate and emtricitabine-triphosphate concentrations in dried blood spots for pre-exposure prophylaxis adherence. J Infect Chemother. 2024 Mar 1:S1341-321X(24)00069-2.
Asako Uchiyama, Yoichi Naritomi, Yoshitaka Hashimoto, Takeshi Hanada, Kyoko Watanabe, Kumiko Kitta, Genki Suzuki, Takao Komatsuno & Takahiro Nakamura; Understanding quantitative polymerase chain reaction bioanalysis issues before validation planning: Japan Bioanalysis Forum discussion group. Bioanalysis 2023.1.9: Published online.
Kawagoe J, Maeda Y, Kikuchi R, Takahashi M, Fuchikami J, Tsuji T, Kono Y, Abe S, Yamaguchi K, Koyama N, Nakamura H, Aoshiba K; Differential effects of dexamethasone and roflumilast on asthma in mice with or without short cigarette smoke exposure. Pulm Pharmacol Ther. 70 (2021) 102052.
Jo H., Yagishita S., Hayashi Y., Ryu S., Suzuki M., Kohsaka S., Ueno T., Matsumoto Y., Horinouchi H., Ohe Y., Watanabe S., Motoi N, Yatabe Y., Mano H., Takahashi K., Hamada A.; Comparative Study on the Efficacy and Exposure of Molecular Target Agents in Non-small Cell Lung Cancer PDX Models with Driver Genetic Alterations. Mol Cancer Ther., 21(2), 359-370(2022)
2021年
Yoshiharu Hayashi, Mayu Ohuchi, Shoraku Ryu, Shigehiro Yagishita, Akinobu Hamada;A procedure for method development and protein binding ratio as the indicator of sensitivity with anticancer agents on MALDI mass spectrometry imaging. Drug Metabolism and Pharmacokinetics, Volume 38, June 2021, 100385.
Hiroyuki Saito, Ryuichi Kambayashi, Mihoko Hagiwara-Nagasawa, Yoshio Nunoi, Ai Goto, Hiroko Izumi-Nakaseko, Shinichi Kawai, Yoshinori Takei, Akio Matsumoto, Kiyotaka Hoshiai , Yasuki Akie, Atsushi Sugiyama;In vivo comparison of dl-sotalol-induced electrocardiographic responses among halothane anesthesia, isoflurane anesthesia with nitrous oxide, and conscious state. Journal of Pharmacological Sciences (2021) 145, 16-22.
Hiroyuki Saito, Ryuichi Kambayashi, Ai Goto, Mihoko Hagiwara-Nagasawa, Kiyotaka Hoshiai, Yoshio Nunoi, Hiroko Izumi-Nakaseko, Yasuki Akie, Yoshinori Takei, Akio Matsumoto, Atsushi Sugiyama; In vivo analysis of concentration-dependent effects of halothane or isoflurane inhalation on the electrocardiographic and hemodynamic variables in dogs. Journal of Pharmacological Sciences (2021) 145, 268-272.
Takeshi Watanabe, Satoshi Yasuda, Shinji Kusakawa, Takuya Kuroda, Mayumi Futamura, Mitsuhide Ogawa, Hidemi Mochizuki, Eri Kikkawa, Hatsue Furukawa, Masato Nagaoka, Yoji Sato; Multisite studies for validation and improvement of a highly efficient culture assay for detection of undifferentiated human pluripotent stem cells intermingled in cell therapy products. Cytotherapy 23 (2021) 176-183.
Dan D. Levy, Errol Zeiger, Patricia A. Escobar, Atsushi Hakura, Bas-jan M. van der Leede, Masayuki Kato, Martha M. Moore, Kei-ichi Sugiyama; Recommended criteria for the evaluation of bacterial mutagenicity data (Ames test). Mutation Research, Genetic Toxicology and Environmental Mutagenesis, Volume 848, November 2019, 403074.
Dan D. Levy, Errol Zeiger, Patricia A. Escobar, Atsushi Hakura, Bas-jan M. van der Leede, Masayuki Kato, Martha M. Moore, Kei-ichi Sugiyama; Demonstrating laboratory proficiency in bacterial mutagenicity assay for regulatory submission. Mutation Research, Genetic Toxicology and Environmental Mutagenesis, Volume 848, November 2019, 403075.
2019年
Lee N, Maeda K, Fukizawa S, Ieiri I, Tomaru A, Akao H, Takeda K, Iwadare M, Niwa O, Masauji T, Yamane N, Kajinami K, Kusuhara H, Sugiyama Y.; Microdosing clinical study to clarify pharmacokinetic and pharmacogenetic characteristics of atorvastatin in Japanese hypercholesterolemic patients. Drug Metab Pharmacokinet. 2019 Dec;34(6):387-395. DOI: 10.1016/j.dmpk.2019.08.004.
Iwamoto N, Takanashi M, Shimada T, Sasaki J, Hamada A.; Comparison of Bevacizumab Quantification Results in Plasma of Non-small Cell Lung Cancer Patients Using Bioanalytical Techniques Between LC-MS/MS, ELISA, and Microfluidic-based Immunoassay. The AAPS Journal (2019) 21:101. DOI: 10.1208/s12248-019-0369-z.
2018年
Genda T, Kondo T, Sugiura S, Hino S, Shimamoto S, Nakamura T, Ukita S, Morita T.; Bacterial Fermentation of Water-Soluble Cellulose Acetate Raises Large-Bowel Acetate and Propionate and Decreases Plasma Cholesterol Concentrations in Rats. J Agric Food Chem. 2018 Nov 14;66(45):11909-11916.
Lemecha M, Morino K, Seifu D, Imamura T, Nakagawa F, Nagata A, Okamato T, Sekine O, Ugi S, Maegawa H.; Improved glucose metabolism by Eragrostis tef potentially through beige adipocyte formation and attenuating adipose tissue inflammation. PLoS One. 2018 Aug 2;13(8):e0201661.
Tsuchiya K, et al.; High-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of raltegravir, dolutegravir, and elvitegravir concentrations in human plasma and cerebrospinal fluid samples. Biomed Chromatogr. 2018 Feb; 32(2). doi: 10.1002/bmc.4058.
Ando K., Takahara A., Nakamura Y., Wada T., Chiba K., Goto A., Lubna N.J., Hagiwara-Nagasawa M., Izumi-Nakaseko H., Hoshiai K., Akie Y., Naito A.T., Sugiyama A.; Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs. J Pharm Sci. 2018 Feb; 136(2): 86-92.
Yokoyama H., Nakamura Y., Saito H., Nagayama Y., Hoshiai K., Wada T., Izumi-Nakaseko H., Ando K., Akie Y., Sugiyama A.; Pharmacological characterization of microminipig as a model to assess the drug-induced cardiovascular responses for non-clinical toxicity and/or safety pharmacology studies. J Toxicol Sci. 2017 42 (1); 93-101.
Okada T., Morino K., Nakagawa F., Tawa M., Kondo K., Sekine O., Imamura T., Okamura T., Ugi S., Maegawa H.; N-3 Polyunsaturated Fatty Acids Decrease the Protein Expression of Soluble Epoxide Hydrolase via Oxidative Stress-Induced P38 Kinase in Rat Endothelial Cells. Nutrients. 2017 Jun 24; 9(7).
Sato D., Morino K., Nakagawa F., Murata K., Sekine O., Beppu F., Gotoh N., Ugi S., Maegawa H.; Acute Effect of Metformin on Postprandial Hypertriglyceridemia through Delayed Gastric Emptying. Int. J. Mol. Sci. 2017 Jun 16; 18(6).
Nagatomo A., Oguri M., Nishida N., Ogawa M., Ichikawa A., Tanaka-Azuma Y.; Evaluation of genotoxicity and subchronic toxicity of standardized rose hip extract. Hum Exp Toxicology 2017; 1-17.
Goto R., Miyakawa S., Inomata E., Takami T., Yamaura J., Nakamura Y.; De novo sequencing of highly modified therapeutic oligonucleotides by hydrophobic tag sequencing coupled with LC-MS. J Mass Spectrom. 2017 Feb; 52(2): 78-93.
2016年
Nakagawa-Yagi Y., Hara H., Nakagawa F., Sato M. and Hara A.; Acute exposure to an electric field induces changes in human plasma 9-HODE, 13-HODE, and immunoreactive substance P levels: Insight into the molecular mechanisms of electric field therapy. Integrative Molecular Medicine, 2016; Volume 3(2), 600-605
2015年
Akiyama H., Matsuoka H., Okuyama T., Higashi K., Toida T., Komatsu H., Sugita-Konishi Y., Kobori S., Kodama Y., Yoshida M., Endou H.; The Acute Encephalopathy Induced by Intake of Sugihiratake Mushroom in the Patients with Renal Damage Might Be Associated with the Intoxication of Cyanide and Thiocyanate. Food Safety. 2015; Vol. 3, No. 1, 16-29
Kitaguchi T., Moriyama Y., Taniguchi T., Ojima A., Ando H, Uda T., Otabe K., Oguchi M., Shimizu S., Saito H., Morita M., Toratani A., Asayama M., Yamamoto W., Matsumoto E., Saji D. et al.; CSAHi study: Evaluation of multi-electrode array in combination with human iPS cell-derived cardiomyocytes to predict drug-induced QT prolongation and arrhythmia- Effects of 7 reference compounds at 10 facilities. Journal of pharmacological and Toxicological Methods. Volume 78, March-April 2015, pages 93-102
Abe H, Ohishi T, Nakane F, Shiraki A, Tanaka T, Yoshida T, Shibutani M.; Exposure to MnCl2·4H2O during development induces activation of microglial and perivascular macrophage populations in the hippocampal dentate gyrus of rats. J Appl Toxicol. 2015 May;35(5):529-35.
Tanaka Y., Kume S., Araki H., Nakazawa J., Chin-Kanasaki M., Araki S., Nakagawa F., Koya D., Haneda M., Maegawa H., Uzu T.; 1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells. Free Radical Biology and Medicine, 89: 831-841 (2015).
Nagayama K., Morino K., Sekine O., Nakagawa F., Ishikado A., Iwasaki H., Okada T., Tawa M., Sato .D, Imamura T., Okamura T., Maegawa H.; Duality of n-3 Polyunsaturated Fatty Acids on Mcp-1 Expression in Vascular Smooth Muscle: A Potential Role of 4-Hydroxy Hexenal. Nutrients, 7(9): 8112-8126 (2015).
Goto R., Nakamura Y., Takami T., Sanke T., Tozuka Z.; Quantitative LC-MS/MS Analysis of Proteins Involved in Metastasis of Breast Cancer. PLoS One, Jul 15; 10(7): e0130760 (2015).